The current work is related to development of sensors for contamination detection, and systems, which use fog as a cleaning agent, in order to prevent disasters and accidents, and to help acting against terrorist attacks and weapons of mass destruction. Investigations in laboratory conditions of several types of mist generators are presented. For this purpose, various products, which create aerosols, were researched. The diameter distributions of the droplets, produced by them, were experimentally determined. For development purposes, several simple devices for easy fog generation are chosen. This study is related to the development of sensors for fog with different characteristics. The obtained results allow a proper selection of sprayers to be made, so that the necessary conditions for the development of sensors are ensured.