Due to intentions of Ukrainian economy to join European Union there are many threats and opportunities on the way. Ukraine has a number of industries producing goods, products and services needed in Europe. The growth of economic ties with EU makes Ukrainian manufactures stronger and has become a question of key importance during last decade. Meantime, Ukraine remains within rather tense conditions of technological lag but with some promising abilities in agriculture and food industries supplemented with a great potential in area of information technologies. This distinctive combination of abilities make it feasible for Ukraine both to become a strong partner for EU and to do a great leap of industrial progress within “Industry 4.0” concept. Nevertheless, one of crucial problems for Ukraine is to build an innovative infrastructure to meet requirements of intellectual transport system conforming to EU “Industry 4.0”. This research paper is focused on discussion of these new features of transport industry and opportunities for Ukraine to make its transport industry a leading advantage for the whole economy. Those drastic changes in Ukrainian transport would procure an excellence for other industries implementing “Industry 4.0”, the same as to become a test ground and an exclusive source of experience for EU on “Industry 4.0” implementation.