Nowadays online learning is among the most progressive and most popular educational practices in the world. Both European and United States universities try to implement this way of learning into the educational process. Further development and popularity, the continued blended learning implementation in Ukrainian higher education institutions, requires high-quality new online courses in various fields of knowledge, adaptations and translations of existing courses for the further leading teaching methodologies used in the educational process. Among the best courses in the world for teaching and learning computer science’s basics is “CS50 Introduction to Computer Science” by Harvard University and professor David J. Malan. This course was translated in Ukrainian and introduces in the blended format in top-rated Ukrainian higher educational facilities. The comprehensive analysis makes possible further blended learning implementation in the technical educational process in Ukraine.