The interrelation between innovation infrastructure of small businesses support with the creation and development of business incubators is analyzed. Imperfect system of funding and material and technical support development of business in Ukraine is established. It was determined that small and medium business accelerates economic restricting, improve organizational efficiency of national resources. So the creation of business incubators is very important for business and sustainable development in the economic situation of the country. The authors give the basic principles of state policy building for small businesses. Foreign experience in creation and development of business incubators is adapted to local conditions by combining and combining different forms, methods and means of regulation and support domestic enterprises. The authors propose the business incubator model which may promote development and management small business.