Study of Vitamin C stability in thermal water for ecofriendly application in the pharmaceutical industry

  • 1 University of Novi Sad Faculty of Sciences, Department of Chemistry, Biochemistry and Environmental Protection, Novi Sad, Serbia


Free radicals and reactive species of oxygen are destructive for living organisms. Antioxidants are capable to reduce the effect of free radicals and to recover the organisms’ health. On the other hand, during the fabrication process various chemicals are released into the water ecosystems from the factories, causing harmful effects on the aquatic organisms. The Autonomous Province of Vojvodina in Serbia is rich in thermal waters. Thankfully to the various minerals, they could have antioxidant effect and could be used as raw material for the production of different pharmaceutical products. In this study we examined the possible effect of different thermal water samples on the degradation rate of Vitamin C as an antioxidant with UV radiation. Furthermore, the influence of initial pH value was also investigated. Our results showed that the thermal water reduced the degradation rate of vitamin C. In addition, the lowest removal rate was observed at initial pH 7, which is close to the skin’s natural pH. These findings showed that the thermal water could be used in preparations for skin.



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