New optical method in laser phototherapy

  • 1 Institute of Electronics, Bulgarian Academy of Sciences, Sofia, Bulgaria


In this study we investigate the kinetics of oxygen tension pО2) in skin tissue under the influence of the transcutaneous laser irradiation. The results of in vivo experimental measurements of pО2 by a method of transcutaneous oxygen monitoring (TcOM) are presented. The results show that under laser irradiation the value of tissue oxygenation increases and after approximately 10 minutes of exposure exceeds its initial level up to 1.6 times. The observed increase in pO2 indicates the process of photodissociation of oxyhemoglobin (HbO2) in skin blood vessels, which results in local O2 increase in the tissue. Such laser-induced enrichment of tissue oxygenation can be used in phototherapy of pathologies, where the elimination of local tissue hypoxia is critical.



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