The aim of this study was to determine the effects of different tillage methods on weeds population in second crop soybean production. The experiment was conducted at the experimental area of Agrıcultural Faculty at Dicle University in 2014. The treatment was lay out at the randomized complete blocks design with three times replication. In this study, different six tillage method were applied (one conventional tillage (CT) – four conservation tillage (RT) and direct sowing (NT)). There were observed more density the species of Xanthium strumarium subsp., Solanum nigrum L., Euphorbia helioscopia L., Convolvulus arvensis L. and Sorghum halepense (L.) Pers in experimental area than other weed species. According to results, there were found significant difference between treatments. The lowest values of weeds were recorded in the conventional tillage methods (CT), while the highest values of weeds were noted in RT4 Tillage methods and NT. Therefore, conventional tillage method was beneficial and useful in reducing of weeds population on soybean crop.