Modelling, Simulation, and Prototyping of Hollow Microfluidic Channel for Investigation of Blood Cells

  • 1 Institute of Mechanics, Bulgarian Academy of Sciences, Acad. G. Bonchev, Sofia, Bulgaria; Center of Competence at Mechatronics and Clean Technologies – MIRACle, Sofia, Bulgaria


The current publication presents an approach for the elaboration of a disposable microfluidic hollow micro-channel using 2 photon polymerization technology and Photonic Professional GT2 (Nanoscribe, Germany) equipment. The design of a 3D model of a microchannel is realized by the CAD analysis software – SOLIDWORKS. A suitable laminar flow is generated by using computational fluid dynamics (CFD) software. As a result, the critical points of the pressure, velocity, and wall shear stress into the microfluidic channel are obtained. A real prototype of the hollow microfluidic device is created, using a highly innovative technology of 3D nanoprinting by twophoton polymerization. Experimental studies with dilute erythrocyte suspensions are conducted to test the functionality of the developed prototype of nano 3D printed microchannel.



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