Mathematical Modeling
Vol. 7 (2023), Issue 3, pg(s) 94-97

MATHEMATICAL MODELLING OF MEDICAL-BIOLOGICAL PROCESSES AND SYSTEMS

Modelling, Simulation, and Prototyping of Hollow Microfluidic Channel for Investigation of Blood Cells

  • 1 Institute of Mechanics, Bulgarian Academy of Sciences, Acad. G. Bonchev, Sofia, Bulgaria; Center of Competence at Mechatronics and Clean Technologies – MIRACle, Sofia, Bulgaria

Abstract

The current publication presents an approach for the elaboration of a disposable microfluidic hollow micro-channel using 2 photon polymerization technology and Photonic Professional GT2 (Nanoscribe, Germany) equipment. The design of a 3D model of a microchannel is realized by the CAD analysis software – SOLIDWORKS. A suitable laminar flow is generated by using computational fluid dynamics (CFD) software. As a result, the critical points of the pressure, velocity, and wall shear stress into the microfluidic channel are obtained. A real prototype of the hollow microfluidic device is created, using a highly innovative technology of 3D nanoprinting by twophoton polymerization. Experimental studies with dilute erythrocyte suspensions are conducted to test the functionality of the developed prototype of nano 3D printed microchannel.

Keywords

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