In this paper is presented an exergy analysis of steam turbine (along with analysis of each cylinder and cylinder part) from ultrasupercritical power plant. Observation of all the cylinders shows that IPC (Intermediate Pressure Cylinder) is the dominant mechanical power producer (it produces mechanical power equal to 394.44 MW), it has the lowest exergy loss and simultaneously the highest exergy efficiency (equal to 95.84%). HPC (High Pressure Cylinder) has a very high exergy efficiency equal to 92.37% what confirms that ultrasupercritical steam process is very beneficial for the HPC (and whole steam turbine) operation. LPC (Low Pressure Cylinder) is a dissymmetrical dual flow cylinder, so both of its parts (left and right part) did not produce the same mechanical power, did not have the same exergy loss, but their exergy efficiency is very similar and in a range of entire LPC exergy efficiency (around 82.5%). Whole observed steam turbine produces mechanical power equal to 928.03 MW, has exergy loss equal to 93.45 MW and has exergy efficiency equal to 90.85%. The exergy efficiency of the whole analyzed steam turbine is much higher in comparison to other steam turbines from various conventional power plants.